The Science of Signal Advance, Inc.

A physical phenomenon referred to as Negative Group Delay (NGD), demonstrated in simple electronic circuits, has been shown to temporally advance the detection of analog waveforms. Specifically, the output is advanced in time relative to the input, as the time delay through the circuit is negative.

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Investing in Signal Advance, Inc.

Information for investors, including SEC filings and executive summary.

Resources

Partnering with Signal Advance, Inc.

Signal Advance, Inc is actively seeking strategic partners to pursue implementation of our proprietary technology in the broad range of application areas. We provide our partners a competitive market advantage.

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Analog Guard® — Physical-Layer Encryption from Signal Advance

Effective January 1, 2026, Signal Advance transferred its Analog Guard® encryption technology and related patents into Analog Guard, Inc., a newly formed, wholly-owned subsidiary. Analog Guard is a hardware-rooted encryption platform that protects data at the physical signal layer rather than in software — a fundamentally different approach designed to resist the remote-hacking techniques that defeat conventional digital encryption. The portfolio includes three issued U.S. patents, a fourth allowed application, and international filings in China, Germany, and India.

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A metaphor

Check this section to understand our technology through a very simple analogy.

Medical

The applications of our technology in the medical field are numerous. Check this section to learn more.

Media / News

Signal Advance has been extensively mentioned in the media. Check our media / news section.

Industrial

There are several non-medical markets for our technology including Energy, Transportation, Process Control/Manufacturing, Communications and Defense.

Awards

1st Prize – Goradia Innovation Competition

2012 Innovator of the Year – Intellectual Property Section, Oklahoma Bar Association

2015 Inventor of the Year – State Bar of Texas Intellectual Property Section

Testimonials

“The State Bar of Texas Intellectual Property Section Recognizes Dr. Chris M. Hymel, Signal Advance, Inc., as the 2015 Inventor of Year.” State Bar of Texas

“It is my belief that Signal Advance® technology will likely be seen as a disruptive technology that forces rapid change in the field of biomedical instrumentation with early adopters of this technology gaining a significant commercial advantage over later adopters in the same field.”

Harold L Russell, PhD

NeuroMedics Technology, Inc.

“Including the projected, risk-adjusted licensing royalties, we project A NET PRESENT VALUE OF UP TO ~$10.4 MILLION. This valuation will increase rapidly as the technology is proven and then successfully applied to products in this very large market.”
(Valuation was based on only two medical applications)

Stephen Weeks, PhD

First Principals, Inc.

“The technology of Signal Advance may well be the key to such effective seizure suppression.” H. Martin Blacker, MD

Neurosurgeon